Sentence examples for modifications in chromatin from inspiring English sources

Activation of the VDR-RXR complex at the OC VDRE occurs through modifications in chromatin mediated in part by interaction of OC gene regulatory sequences with the nuclear matrix-associated Cbfa1 (Runx2) transcription factor which is required for osteogenesis.

Domain architectures of the primary enzymes involved in the eukaryotic protein methylation system indicate key features relating to interactions with each other and other modifications in chromatin, such as acetylation.

Histone modifications in chromatin regulate gene expression.

This process is regulated by modifications in chromatin remodelling, mainly H3K4me3 in HLA-B, and β2m, as well as H3K9me3 in TPN gene, respectively.

Notwithstanding the importance of histone modifications in chromatin regulation in plants, only the N-terminal modifications on Arabidopsis histone H3 have been systematically analyzed by mass spectrometry combined with chromatographic separation [28].

These modifications in chromatin structure may be activating much of the new miRNAs detected in the present study.

The results revealed that the chromatin modification intensities in T2D-related differentially methylated genes were much higher than those in non-differentially methylated genes, indicating the specific pattern of chromatin modifications in T2D.

Chromatin structure influences splicing choices but splicing can also actively modulate the pattern of histone modification in chromatin.

Histone methylation is an important epigenetic modification in chromatin.

The plenary lecture by Steven Jacobssen reviewed the status of epigenetic modification in chromatin and the general issue of gene silencing in plants.

Undoubtedly, the discovery of hydroxylation as a mechanism to revert N-methylation found in nucleic acids or proteins is a milestone that has triggered substantial progress in identifying the role of this post-translational modification in chromatin biology, and defining epigenomic elements in genome biology in general.