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The next era in fertility preservation research will be focusing on the pharmacological and genetic modifications in both slowing down oocyte attrition and enabling a healthier ovarian niche.
Some reports demonstrated that changes in cell shape precede and trigger dramatic modifications in both gene expression and enzymatic function.
The oxidised samples showed increases in oxidative modifications in both alpha and beta chains, commonly methionine sulfoxide and tyrosine nitration, correlating with increasing SIN-1 treatment.
Expression analysis, gene-targeted knockdown experiments and in vitro catalytic assays indicate that zebrafish Stx is the principal if not unique polysialyltransferase performing NCAM-PSA modifications in both developing and adult fish.
Although there are some common structural features of peptidoglycan, there is large variability in the structure of bacterial peptidoglycan due to differences in the amino acid sequence, types of cross-links, and the presence or absence of secondary modifications in both the glycan strands and peptides.
In addition, ectopic expression of wildtype FLCN and FLCN/FNIP1 induced post-translational modifications in both TFE3 proteins in UOK257 cells (Fig. 3C, lanes 3 and 5).
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According to the thrombin time test, the aptamer with thio-modifications in both TT loops (LL11) exhibits the same antithrombin efficiency as the original TBA.
Lysine acetylation is a widespread and highly conserved post-translational modification in both eukaryotes and prokaryotes with multiple functions (Choudhary et al. 2009; Wang et al. 2010).
Changing foot landing position appears to significantly alter lower extremity biomechanics for both men and women during a double-leg jump and can be a target for movement pattern modification in both sexes.
The intense decomposition sustained by the bio-plastic strips during the composting tests hampered a suitable collection of residual fragments for the gravimetric analysis at the final experimental time, thereby suggesting severe physical fragmentation and chemical modification in both decomposition tests with 1 and 2 % of bio-film concentration (Additional file 1: Figure S1d).
Subsequent physiological experiments showed that learning produces prolonged synaptic modification in both of the inputs to the amygdala: the thalamo-amygdala pathway [11], [12] and the cortico-amygdala pathway [13].
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com