Sentence examples for modifications have revealed from inspiring English sources
Meanwhile, other bridging, as well as non-bridging, modifications have revealed intriguing possibilities for new drug design.
Strong epigenetic influences have also been described, and in particular histone modifications have revealed associations with hyperglycemia and pro-inflammatory phenotypic relevance for diabetic complications.
In parallel, technologies enabling the genome-wide profiling of histone modifications have revealed the existence of noncoding driver genetic alterations in cancer.
Genome-wide analyses of chromatin modifications have revealed a complex landscape of modified histones at transcription start sites (TSSs), distal regulatory elements and conserved sequences.
Systematic studies of chromatin modifications have revealed a complex landscape including 'punctate' sites of modified histones (histone H3 lysine 9/14 acetylation and lysine 4 di- and trimethylation) at transcription start sites and distal regulatory elements [9], [10].
Remark 3. Analysis of the group Lasso and its modifications has revealed that its performance can be close to the Schwarz-regularized LS either when the regression matrix is sufficiently block incoherent, or, when the block restricted isometry property holds [10, 27].
Systematic analysis of histone modifications has revealed a plethora of posttranslational modifications that mediate changes in chromatin structure and gene expression.
In addition, such genetic modification experiments have revealed that the reactions ascribed to specific OMTs, based on catalytic activity with supposed substrates in vitro, are not necessarily the preferred reactions for these enzymes in vivo.
Previous chemical modification studies have revealed that none of CTs' loops is exclusively responsible for biological activities of the toxins [45] [47].
Our substrate modification studies have revealed occult epoxidase and 21-hydroxylase activities of CYP17A1, and the fraction of epoxide formed correlated with the 16α-hydroxylase activity of the enzymes.
Recent studies of the proteins involved in the elaborate post-translational modifications of lantibiotics have revealed that these enzymes have relaxed substrate specificity.
