Sentence examples for modifications have been shown from inspiring English sources

Epigenetic mechanisms, particularly DNA methylation and histone modifications, have been shown to play an important role in regulating such plasticity.

Indeed, both cell division timing and histone modifications have been shown to affect cell fate decision in preimplantation embryos (Zernicka-Goetz, 2006).

As a classical approach to modifying the properties of polymers, wet chemical modifications have been shown to induce the presence of reactive functional groups at the surface of polymer membranes (Liston et al. 1994).

Histone modifications have been shown previously to be one mechanism of modulating transcription factors (TFs) and transcriptional control [6], [7].

Epigenetic modifications have been shown to affect gene expression patterns and often contribute to the pathogenesis of many cancers [4].

Physiologically similar local modifications have been shown in the form of a slight decrease in fEPSP, after behavioural conditioning [68].

Recently, a histone signature comprising 17 modifications has been shown to mark the transcriptional start sites of highly expressed genes in T lymphocytes [38].

The implementation and removal of these post-translational modifications has been shown to be fundamental to the regulation of diverse biological processes such as DNA replication, repair and transcription [6].

Health intervention program (HIP) based on diet and lifestyle modifications had been shown to improve cardiovascular risks.

Altering optimum pH by structural modifications has been shown by Neves-Petersen et al. using the triglyceride lipase/cutinase from Fusarium solani pisi [ 86].

Moreover, none of the other transcription-mediated histone modifications has been shown to directly increase the accessibility of DNA in nucleosomes.