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All these modifications have been implicated during oxidative stress, aging and age-related diseases.
There is no published data that show that any of the crib modification products prevent injury, or even save the furniture, but there is plenty of data showing that these modifications have been implicated in the deaths of babies and toddlers in their sleep space.
In the human malaria parasites Plasmodium falciparum, histone modifications have been implicated in the transcriptional regulation.
Similar to other eukaryotic organisms, in the human malaria parasite Plasmodium falciparum, histone modifications have been implicated in chromatin remodeling and transcriptional regulation [1], [2], [3], [4], [5], [6].
Histone modifications have been implicated in the regulation of transcription and, more recently, in DNA replication and repair.
More recently, HDL protein modifications have been implicated as pathogenic factors directly or indirectly involved in atherosclerosis diseases.
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Consequently, dysregulation of the balance between these two modifications has been implicated in cancer, diabetes, and neurodegenerative disease.
Additionally, the expression level of BRD4 phosphorylated on serine residues 484 and 488 (BRD4 pS484/488) was also measured as post-translational modification has been implicated in the regulation of BRD4 function21, 34, 35, 42.
This post-translational modification has been implicated in protein sorting, trafficking and dynamics in different cells [ 45].
Histone modification has been implicated as an important process for controlling gene expression (Li et al. 2007).
In addition, epigenetic modification of the E-cadherin genes including DNA methylation and histone modification has been implicated in E-cadherin expression.
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