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This number of different modifications has a high combinatorial potential, which would yield a hugely complex histone code [22] and it is under debate, whether such a code exists or whether histone modifications are a consequence and mere reflection of dynamic processes altering DNA accessibility such as transcription factor or RNA polymerase II (RNAPII) binding or chromatin remodeling [23].
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Additionally, combination of these surface modifications has an additive effect on cell proliferation.
This shows that both modifications have a positive impact on the GPS receiver performance.
In general the cycle modifications have a positive effect on the overall COP of the system.
Results show that the modifications have a large influence on the characteristics and carbonization behavior of the CTP.
The deterministic models require an enormous number of operating environment information and huge computational effort, while semi-empirical models obtained as their empirical modifications have a moderate complexity.
Both of these modifications have a crucial role in the folding, acquisition of the functional capacity, and later appropriate sorting of the SI molecules to the BBM [5].
Both of these protein post-translational modifications have a role in signal transduction [43].
Toxins may alter target protein function by specific modifications, having a major impact on cell survival.
This means that large, bulky post-translational modifications have a big impact on their binding properties.
Interestingly, all modifications had a higher sensitivity than the WHO classification system.
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