Sentence examples for modifications gene expression from inspiring English sources

Cells deplete nutrients and respond to the environment and its dynamics with changes in metabolic fluxes, post-translational modifications, gene expression, quorum signaling and synthesis of storage compounds.

In addition to DNA methylation and histone modifications, gene expression is also regulated by microRNAs (miRNA); the small noncoding RNAs that regulate gene expression posttranscriptionally by binding to complementary sequences in the 3′ untranslated regions of messenger RNAs [ 43, 44].

Epigenetic mechanisms, including DNA methylation and histone modifications, change gene expression without alteration of the DNA sequence itself.

Thus, our findings suggest that alterations in chromatin modification gene expression might contribute to endothelial dysfunction and provide a possible mechanistic link between each metabolite and atherothrombosis.

While the nature of the enzyme isotype is intrinsic properties which can be alter by genetic modification, gene expression and regulation might be easily affected by environmental factors [ 19, 20].

The important role of the WMM complex in the regulation of m6A modification, gene expression and mRNA processing in cultured cells prompted us to investigate its functions at the organismal level using zebrafish embryos as the model system.

One adaptive mechanism to help modulate stress response is to act through subtle modifications of gene expression, primarily through epigenetic mechanisms such as methylation and histone modifications.

We have recognized the association of different epigenetic modifications with gene expression, but the triggers for the differential marking of epigenetic modifications throughout the genome is largely unclear.

Modifications in gene expression are controlled by fundamental epigenetic mechanisms including DNA methylation, histone modifications, chromatin remodeling and microRNAs that act as regulatory molecules.

This refers to functionally relevant modifications to gene expression that do not involve a change in nucleotide sequence.

Szyf reviews epigenetic modification through the modification of gene expression through regional DNA hypermethylation in chapter 10.