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However, such modifications failed to clarify ROS-initiated cellular signaling.
However, these modifications failed to increase the net FA production [ 21].
The H NMR experiment with the C+TGA+TA+TGC sequence that contains only isolated LNA modifications failed to show significant changes in base stacking.
In contrast, multiple antibodies against common histones, centromere-specific histones, or histone modifications failed to decorate PICH-positive threads, raising the question of whether the DNA in these threads is associated with any histones (Baumann et al. 2007; Chan et al. 2007; Wang and Nigg, unpublished results).
The absence of PRC1 in plants seemed an obvious conclusion as an initial screen of Arabidopsis thaliana histone modifications failed to find a ubiquitinated H2A residue [ 5], a hallmark of PRC1, and because orthologs of crucial PRC1 subunits were initially not detected in A. thaliana or other plant genomes [ 6].
Similar(54)
However, an increasing number of studies have provided evidence suggesting that these Keap1 redox modifications fail to disrupt the Nrf2/Keap1 complex.
However, in the majority of patients with T2DM, lifestyle modifications fail to achieve or maintain glycemic goals due to a combination of factors, including the failure to lose weight, weight regain, or progressive disease.
Despite the substantial peptide identifications derived from MUC16, the lack of identified peptides (red rectangles) overlapping glycosylation sites (black bars) demonstrates that domains containing glycan modifications fail to be identified in a traditional shotgun proteomic analysis.
Moreover, unlike wild-type AGS3, over-expression of an AGS3 mutant lacking this modification fails to enhance macroautophagic activity.
When lifestyle modification fails to achieve adequate glycemic control, medical intervention is recommended.
When lifestyle modification fails to achieve adequate glycemic control, medical intervention is often necessary.
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Justyna Jupowicz-Kozak
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