Sentence examples for modifications established from inspiring English sources

Both the maternally and paternally derived genomes in the embryo favor maintenance of the epigenetic modifications established in the female and male germlines, respectively.

Functional differentiation of chromatin structure is regulated by multiple and hierarchical epigenetic modifications established at critical developmental transitions by chromatin remodeling proteins and histone post-translational modifications.

Some peculiarities of the silicas pore structure are discussed on the basis of the different behaviour of their metal oxide modifications established by the combined physicochemical and catalytic investigations.

The subsequent maps of transcription factor binding, chromatin structure, and modifications established by ChIP-chip and similar assays have greatly broadened our understanding of mechanisms regulating transcription [2] [9].

The repressed status, often referred to as poised, is conferred by epigenetic modifications established at loci encoding developmental regulators.

Imprinting has been documented in insects, plants, mammals, and nematode worms (Anaka et al. 2009; Golic et al. 1998; Lloyd et al. 1999; Maggert and Golic 2002; Renfree et al. 2013; Sha and Fire 2005; Singh 1994) and is mediated by DNA methylation and histone modifications established during oogenesis and spermatogenesis (Sha 2008).

They said that New York State should plan better, by adopting multiyear budgets with quarterly modifications; establish an independent, nonpartisan office to watch over fiscal deliberations; require the Legislature to adopt a budget on time; and add to the "rainy day" fund so that more money is available during economic downturns.

Patterns of histone post-translational modifications (PTMs) and DNA modifications establish a landscape of chromatin states with regulatory impact on gene expression, cell differentiation and development.

Histone modifications establish the chromatin states that coordinate the DNA damage response.

The incorporation of histone variants into specific genomic regions by their corresponding chaperones and chromatin assembly pathways, together with the particular patterns of histone post-translational modifications establish heterochromatin domains required for genome integrity and the formation of cell type-specific chromatin landscapes.

The study also aims to analyse the mutations which appeared through evolution process of residential buildings and identify the invariant elements and the main trajectories of modification established in the past, confirming their compatibility with the future development of Aleppo.