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While only a few defined factors can trigger induction of pluripotency, the underlying mechanisms are complex, including the up/downregulation of transcription factors, a wide array of epigenetic changes, protein post-translational modifications, effects mediated by micro-RNAs, and adaptations in cellular signaling and cell-to-cell communication.
Because sex hormone receptors and X inactivation escape genes together include transcription factors and genes involved in post-translational protein modifications, effects of sex differences will propagate downstream to affect many pathways and cellular processes.
We looked for randomized trials, observational and retrospective studies, original works, and review articles having topics as the relation between male HPV sperm infection, seminal modifications, effects on fertilized oocytes, association to apoptosis, early miscarriages, and implications on male and couple reproductive outcomes.
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But more mechanistic insight is still needed in order to understand how epigenetic modifications effect their biological functions.
The modification effects of single and combined polymers were investigated.
Flow modification effects are apparent to extremely low concentration (≈c∗/100).
Typical interstitial modification effects are observed in PrFe12−xVxN1.6.
The modification effects of the EQs on the ionosphere seem to be diverse.
As shown in Fig. 2, visual modification effects have been observed.
However, different types of fluorine-containing compounds may have different modification effects.
Amylose content and chemical modification effects on the extrusion of thermoplastic starch from maize.
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