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Exact(5)
There are numerous possibilities to explain the manner in which these modifications could occur.
However, it remains unknown whether FLC chromatin can simultaneously carry these two modifications as it is formally possible that these modifications could occur in two subpopulations of FLC chromatin and not in the same physical region of FLC.
From one point of view all these modifications could occur after the release of HMGB1 within the injured tissues.
This finding indicates that these protein modifications could occur at a postranscriptional level and illustrates the importance of assesing protein changes through various means, and not relying solely on mRNA levels [ 38].
It is interesting to note that the control sample (without light stress) already contained small yet detectable amount of cross-linking (0.4%, Figure S1D in the Supporting Information), suggesting such modifications could occur during routine protein production and process.
Similar(55)
Formation of oxygen-based functional groups onto the polystyrene surface after argon plasma modification could occur via post-oxidation reactions.
The only place this modification could occur is at S36 (Fig. 2B).
Two types of histone modification could occur in an independent or a synergistic manner depending on gene contexts.
This enabled us to identify sulfonic acid modification on Cys-39 after TNM treatment resulting in an irreversible de-activation of complex I. Since sulfonic acid modification could occur in vivo upon oxidative stress [46] complex I could be arrested in the D-form resulting in complex I deficiency.
This parameter averages the modifications that could occur in the distribution of the signal intensities.
For each core histone peak eluting from the LC, we selected a specific mass range that encompassed all of its isoforms in an unmodified state as well as the possible spectrum of modifications that could occur.
Related(20)
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