Sentence examples for modifications chromatin structure from inspiring English sources
Histone modifications, chromatin structure and binding activity of EZH2 to the C/EBPβ binding region in the Vegf promoter in rat GCs undergoing luteinization.
In this chapter, we describe the predominant forms of epigenetic regulation (DNA modifications, chromatin structure, and noncoding RNA expression) and discuss the various methodologies used to assess each epigenetic mark.
A variety of epigenetic mechanisms have been identified including DNA methylation, histone modifications, chromatin structure, and selected ncRNA.
These epigenetic mechanisms include DNA methylation, histone modifications, chromatin structure, and selected noncoding RNA (ncRNA) (Skinner 2014a).
Since nucleosomes impact all processes involving the genome, our results provide a link between epigenetic modifications, chromatin structure, and regulatory function.
Although other epigenetic processes such as histone modifications, chromatin structure, and noncoding RNA are also important, DNA methylation is the best known epigenetic process associated with germline-mediated heritability and environmental manipulations (Skinner et al. 2010).
This control includes four interacting molecular components: DNA methylation, post-translational histone modification, chromatin structure and non-coding RNAs.
Conversely, genes related to "RNA processing and modification", "Chromatin structure and dynamics", "Cell motility and Signal transduction mechanisms" (COGs A, B, N, and T, respectively) are absent from Portiera.
A number of uncharacterized transporters were also regulated, as well as genes involved in transcription, RNA processing and modification, chromatin structure and dynamics, and DNA replication, recombination, and repair.
Polycomb group (PcG) proteins, as epigenetic regulators of tran-scription through the formation of polycomb repressive complexes containing BMI1 polycomb ring finger proto-oncogene (BMI1) or enhancer of zeste 2 polycomb repressive complex 2 subunit (EZH2), also modulate histone modification, chromatin structure, and CpG methylation levels [42], [43].
Not only do histone modifications influence chromatin structure, but modifications of the DNA itself can also lead to remodelling of chromatin and consequently result in gene silencing.
