Sentence examples for modifications characterised by from inspiring English sources

In vitro experiments have shown previously that SERPINB3 determines morphological modifications characterised by elongated shape and decrease of desmosomal junctions associated with a remarkable accumulation of β-catenin and E-cadherin downregulation (Quarta et al, 2010).

More importantly, these studies also revealed that the vast majority of PML RARalpha-binding sites, associated with distinct histone modifications characterised by low H3-acetylation (H3ac), reduced H3K27 trimethylation (H3K27me3) and increased H3K9me3 (Hoemme et al, 2008; Martens et al, 2010).

RNA editing is a process of post-transcriptional RNA modification characterised by the insertion, deletion or modification of nucleotides [ 1, 2].

The underlying molecular mechanism is believed to involve epigenetic modifications of the genome, characterised by dynamic changes in DNA methylation and noncoding RNAs, as well as diverse patterns of covalent histone modifications.

They are characterised by marked modifications of proteins including synthesis of extracellular matrix proteins, suggesting that proteomics might provide new insights for diagnosis of fibrosis or cirrhosis.

The second cell reactivation phase is therefore characterised by profound modifications to the structure of organelles and different cell compartments, together with increases in both nuclear- (× 1.5) and nucleolar- (× 1.9) volumes as compared to the first cell reactivation phase.

One pattern of chromatin modification not investigated was related to 'poised' or bivalent chromatin typically found in embryonic stem cells, characterised by simultaneous modification with the repressive H3K27me3 mark and the activating H3K3me3 mark (Bernstein et al. 2006).

Chronic RAD001 treatment caused resistance development characterised by distinct modification of the integrin-expression profile, driving prostate cancer cells towards high motility.

This study approach, therefore, provides important implications for palaeohydrographic and palaeoenvironmental reconstructions in a complex area that is characterised by significant geomorphological modifications during the last millennia.

We began by investigating whether stem cells in human interfollicular epidermis were characterised by specific histone modifications.

If the evolution of the cultural artifacts is characterised by descent with modification, such analyses would be justified.