Sentence examples for modifications by integrating from inspiring English sources

Future developments are planned to include additional protein modifications by integrating other resources such as UniProt (Farriol-Mathis et al., 2004).

More recently, Schiml et al. (2014) achieved heritable genome modifications by integrating a resistance gene cassette into an endogenous ADH1 locus via in planta gene targeting after RGEN-mediated DSB induction.

Examining the ENCODE data for the region chr10 112,630,451 112,631,970 (GRCh37/hg19 assembly), the area including rs6585018 G>A has been reported to be rich in active regulatory elements, such as strong active enhancer regions, DNase I hypersensitivity sites and histone modifications as predicted by integrating chromatin immunoprecipitation sequencing (ChIP-seq) data [ Dunham et al., 2012].

In this article, we infer significant modifications of biological activities by integrating the expression differentiation with three sources of biological knowledge: Gene Ontology (GO), KEGG pathways, and cellular localization of proteins.

Lentivirus vectors achieve permanent genetic modification of transduced cells by integrating DNA copies of their genomes into the host cell's chromosomal DNA.

Given the complex nature of gene expression regulation, and the critical roles of epigenetic systems including cytosine modifications (primarily DNA methylation at CpG dinucleotides) in gene regulation and in a broad range of biological processes, our team has undertaken a more comprehensive study of gene regulation by integrating cytosine modifications into the current HapMap resources (9).

By integrating compositional modification, dopant addition and double annealing techniques, good static material properties are obtained, including a room resistance (R25 °C) of 14.3 Ω, a resistivity jump (ρmax/ρmin) of 3.2 × 106, a temperature coefficient of resistance (TCR) of +20.4%/°C, and a maximum operating voltage (Vo) of 357.5 Vrms.

The data suggest that significant differential gene expression can be missed by expression microarray analysis but recaptured by integrating functionally relevant epigenetic modifications such as H3K9 acetylation.

This was done by integrating position of histone modifications, and transcription factors' binding sites at multiple intervals.

Finally, by integrating with eight histone modification marks, DNA methylation, regulatory elements regions, ERα and Pol-II binding activities, associations between epigenetic patterns and high chromosomal interaction frequency were revealed in E2-mediated gene regulation.

By integrating in-host genoma, it induces modifications on cellular cycle proteins.