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Activity and stability of life-supporting proteins are determined not only by their abundance and by post-translational modifications, but also by specific protein protein interactions.
This will not only further improve the robustness under admissible operations and the classification precision of malicious modifications but also be a solution for fragment authentication of audio that has never been scarcely touched in the research community.
The function of p53 and its promoter binding capacity is regulated by a number of posttranslational modifications but also by various cofactors [46], [47] and is therefore largely dependent on the cellular context.
Chromatin conformation is thought to be regulated not only by histone modifications, but also by DNA methylation.
This process, linked to genes' structural features (first intron length), not only actively modulates histone H3 Lys 3 modifications but also improves quality of intron splicing.
This method is widely applicable, not only for epitopes generated by post-translational modifications, but also for epitopes consisting of only standard amino acids.
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Further studies are needed not only to investigate the potential deleterious effects of this modification, but also to define the specific mechanism which underlies such fibrate-mediated action.
This is not surprising, because the changes of H3K4me3 levels are not always correlated with those of other histone modifications18, and because gene expression is regulated by not only one histone modification, but also the combination of various histone modifications13.
Experimental results show that our approach not only can detect and locate malicious topology attacks such as components modification and joint ends modification, but also is robust against various non-malicious attacks such as similarity transformations and simplification.
In particular, new and/or improved approaches have established robust methods that not only allow for in-depth and accurate peptide and protein identification and modification, but also allow for sensitive measurement of relative or absolute quantitation.
The facile strategy disclosed in our study can provide new opportunities to not only nanofiltration membrane modification but also the surface engineering of vast kinds of materials towards energy and environmental applications.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com