Sentence examples for modifications became necessary from inspiring English sources
Modifications became necessary for the instructions of the individualised dyspnoea items of the CRQ-SA.
Dose modifications became necessary in seven out of 18 patients (39%); in three out of 18 patients (17%) treatment had to be stopped completely.
These comments will be considered for a potential update of the document that will be developed if the evidence base has changed substantially and modifications become necessary.
Since there were multiple ways in which we could combine the different modifications, it became necessary to try to reduce the number of possible network realizations, as outlined in Step III.
Common toxicity criteria grade 3 or 4 treatment-related toxicities, as well as all toxicities leading to a dose modification of imatinib, are summarised in Table 5. Grade 3 or 4 toxicities were experienced by five patients (27.8%); dose modifications of imatinib became necessary in seven patients (38.9%).
This new software became necessary for managing all of the patients' identities data modifications, which are now treated with high traceability and practicability.
It became necessary to build a camp.
More frequent tinkering became necessary.
"On occasion, hospitalization became necessary".
"Then it became necessary but not sufficient.
