Sentence examples for modifications at distinct from inspiring English sources

The review also assesses the impact of topographical modifications at distinct dimensions (micrometre and nanometre orders of magnitude) and the importance of applying safe-by-design criteria (e.g. toxicity, contribution for unwanted acquisition of antimicrobial resistance, long-term stability) when developing and implementing antimicrobial surfaces.

Our findings show that although common general mechanisms may be utilized for positive and negative regulation, in a given target gene such as TSHα, different co-factors as well as histone modifications at distinct sites, may determine positive versus negative regulation of transcription.

Modifications found at distinct residues of the histone protein N-termini include - among others - lysine acetylation, lysine and arginine methylation as well as serine and threonine phosphorylation.

The opposing DNA methylation modifications at these distinct regulatory regions may respectively direct the placement of P1-mm in euchromatin and heterochromatin.

Given that certain histone modifications are consistently found at distinct regions of the stereotypical gene, analyzing global patterns of ChIP signal relative to TSSs is a useful method to assess biological validation47.

In addition, and very importantly, sequential ligations allow multiple different modifications to be placed at distinct sites along the polypeptide chain.

Their notation is analogous to that for species, with the sole difference being that the modification 'X' at a specific site indicates that all distinct modifications at this site are included.

Our investigations also showed that both agents, 5-aza-CdR and TSA, were necessary to launch distinct histone modifications at the MAGE-A1 promoter.

Chemical modifications to the cilengitide molecule, including N-methylation at distinct positions, can modulate its biological, structural, and pharmacokinetic properties; this could enhance selectivity, particularly for the αv β3 subtype [ 77].

Intriguingly, chromatin regulators encompassing histone modifiers and histone modification binding proteins are present in a combinatorial fashion at distinct genomic loci and frequently bring together regulators associated with opposing activities [27].

This code might result in distinct combinations SUMO modifications at different sets of lysine residues of Gli proteins with each combination resulting in a different effect on the activity of the Gli protein.