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The presence of PTB masked the RNA, rendering it inaccessible to DMS modifications at certain places.
It is known that egg-adapted influenza viruses tend to have non-natural host-associated modifications at certain sites of HA sequences [62], [63], [64].
Vertebrate tRNAs also have specific modifications at certain positions in their structures that allow innate immune sensors to discriminate between them and bacterial tRNAs (Gehrig et al., 2012).
Modifications at certain threonine/serine residues determine whether CDK9 associates with large P-TEFb complex to become available for recruitment and whether the dissociation of the large complex will efficiently occur.
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Quantitative differences imply that, in a cell population, only a fraction of the cells possess the histone modification at certain positions and that this fraction differs from one strain to another.
This modification at a certain extent decreases the interface area between synthetic material and contact area leading to reduction in the amount of prime volume of the system [ 11].
In this article, the authors present a logical model of protein-protein interactions that allows to take into account the modifications induced by the interaction at certain residues.
Like mRNA, the pri-miRNA transcripts can have certain modifications at their ends (i.e., a "cap" at the 5′-end and multiple adenosine units [i.e., a poly-A tail] at the 3′-end) and can be spliced (Cai et al. 2004 ).
The properties of each monomer were further modified to enhance self-assembly into higher order structure(s) by increasing hydrophobicity at certain positions (Chg/Cha modifications).
A recent paper by Guertin and Lis [31] investigated the distribution of chromatin modifications and certain chromatin proteins at HSEs prior to the binding of HSF in Drosophila.
Furthermore, studies of a choline and methyl-deficient C57BL/6 mouse prostate cancer model suggest that chromatin modifications are more susceptible to methyl-deficient diets than DNA methylation at certain loci [ 48].
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