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In the western Palaearctic, two groups of Coleoptera include the majority of the underground diversity: the tribes Trechini (family Carabidae) and Leptodirini (family Leiodidae), with hundreds of species with different degrees of morphological modifications assumed to be adaptations to the subterranean environment – different degrees of "troglomorphism" [ 2- 4].
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Phosphorylation/dephosphorylation events regulate IP3Rs Ca2+ release and these modifications assume particular relevance in cell death.
The model describes histone modifications assuming a positive feedback between the presence of the histone mark and the recruitment of modifying complexes as demonstrated for H3K4me3.
SBI and DSP modification: Assuming that the corresponding survival branch is initiated from group, for each.
The absorbed dose calculations for the orally administered activity of 99mTc-pertechnetate were performed using the biokinetic model by Leggett and Giussani [36], with a slight modification assuming no uptake in the liver.
These extensive protein modifications are assumed to impair the association of ITGB4 with ITGA6 and other key proteins of the hemidesmosome anchoring complex.
The queuosine modification is assumed to increase accuracy of translation, and change the optimal binding from codons ending in C to no preference or a slight preference for U-ending codons for GUN codons (Ran and Higgs 2010).
An effect modification was assumed to be present based on p-value < 0.05.
If the interaction term was significant in Model 3, effect modification was assumed and sub group analysis was performed.
Effect modification was assumed to be present if the P value for the interaction term was < 0.05.
Similar local modification is assumed for vertebrate limbs (Ruvinsky and Gibson-Brown 2000; Minguillon et al. 2009; Duboc and Logan 2011a; reviewed in Duboc and Logan 2011b).
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