Sentence examples for modifications as demonstrated from inspiring English sources
The molecular weight of 65 kDa as compared to the predicted 59.4 kDa suggested the presence of glycosyl modifications, as demonstrated using a glycosylation detection reagent and a mobility shift of about 5 kDa after PNGase F treatment (data not shown).
A simplified example of structural mining is the discovery of motifs in sequences surrounding a specific site, e.g. for a class of known post-translational modifications, as demonstrated in Figure 3. Biological sequences with the site of interest can be retrieved from public repositories and aligned with the common site as the central anchor point.
OECs normal cell function was unaffected by genetic modification as demonstrated by normal microscopic morphology and the presence of the low affinity neurotrophin receptor (p75NGF) following viral transduction.
Because xylanase has three consensus N-glycosylation sites, the microheterogeneity detected is probably due to post-translational modification, as demonstrated later.
It is possible that SirT1 works in the context of a larger epigenetic modification complex, as demonstrated in the murine Polycomb repressive complex 4 (PRC4) [ 24].
Furthermore, the immune response to mycobacterial infections can be affected by epigenetic modifications, as recently demonstrated in a bacillus Calmette-Guérin infection [ 51], and these mechanisms have been shown to be essential for the development and stability of T helper cells [ 52, 53].
It was found that the addition of clay hybrids reduced LTLP and HTHP fluid loss due to a restructured mode of clay platelet interaction attributed to a modification in surface charge as demonstrated by zeta potential measurements and scanning electron microscope images.
This modification had clinical significance, as demonstrated in this study.
The method provides the ability to crudely loop-shape the adaptive structure, as demonstrated through modification of both the actuator-to-sensor frequency response function and the system loop gain.
Tethering of either HAT domain fusion (tetR-EYFP-p300HD or tetR-EYFP-PCAFHD) to the synthetic alphoid DNA enhanced H3K9ac modification and CENP-A assembly, as demonstrated by time-course ChIP assays.
The modification of protein N-termini by ubiquitin could regulate substrate stability or function in many ways, such as altering the N-degron [ 17], targeting for the UFD (ubiquitin fusion degradation) pathway [ 18] or triggering further modifications such as Lys poly-ubiquitylation as demonstrated in the present study.
