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When the analysis was restricted to animals with HIS of less than 13 grams, Norris and Roberts modifications as compared to Shell's method improved correlation with CPK-MB but reduced correlation using CPK and CPK-MM data.
Consequently, they suffered few modifications as compared to those proteins presenting high evolutionary distance.
However, electron microscopic analysis of the surface of P. chabaudi-infected erythrocytes did not reveal any modifications as compared with nonparasitized erythrocytes.
In IMR90, there is a significant improvement from using the top two modifications as compared with using H3K9ac alone, with difference in TP ranging between 5% and 20% at the same FP.
Similarly a modified RASS (with different modifications as compared with the RASS-PAL) used in Spanish patients with advanced cancer also demonstrated very good inter-rater reliability, especially when used by experienced professionals [ 13].
Improved interaction of FLLL32 with the Src homology-2 (SH2) domain of STAT3, a region instrumental in its dimerization and nuclear translocation, as well as greater stability, was predicted with these modifications as compared to curcumin [ 38, 39].
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Pure water permeability was found to decrease by 33% after surface activation and by ∼70% after chemical modification as compared to that of the unmodified PBI membrane.
Nevertheless, it is interesting to notice that CIS derived from HSC-GT in vivo CD3+ cells displayed a different distribution of this histone modification as compared to NOT CIS subset and to the CD34+ cells in vitro from which they derived.
Rather, it may be the combination of Hmt1-deletion with the loss of another regulator that effects a significant change in histone modification levels as compared to any single loss-of-function mutant.
Centromeric chromatin is associated with distinct histone modification patterns as compared to classical euchromatin and heterochromatin in several model eukaryotes.
Three modifications were performed as compared to the original model (Table 1).
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