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These modifications are removed in favor of H3K27me1 and H3K36me3 as expression levels increase.
Indeed, this finding is consistent with the observation that post-translational modifications of proteins only rarely contribute to the cognate T cell epitopes bound to class II MHC [15], [16], [17], perhaps because these modifications are removed in lysosomes.
Both modifications are removed the PP4 phosphatase.
Our data also suggest that the machinery for the expression of COX-2 and probably other antifibrotic genes in IPF remains intact and functional and can mediate reexpression if the repressive epigenetic modifications are removed.
These observations highlight that the fusion of two heterochromatic micronuclei during conjugation leads to a zygote nucleus, in which all repressive micronuclear-specific histone modifications are removed and permissive histone modifications are introduced de novo.
Similar(54)
In 1998, the film modifications were removed, and the aircraft returned to the original G-2 configuration.
Matches to 6 types of modifications were removed from the analyses, as they are not found in S. cerevisiae or may lead to many false positives due to their low mass; for more details see Additional file 6.
The polymerase must have the proper affinity and selectivity towards modified nucleotides along with adequate turnover rate and propensity to form terminated DNA molecules that remain stable until the 3′-modifications are removed by chemical means.
Any patient requiring further dose modification was removed from the study.
The sample was lightly scratched using a pair of tweezers, applying not enough force to damage the surface of the silicon wafer, thus, ensuring that only the hydrogel and the CVD modification is removed.
The significance of this covalent histone modification sits at the juncture between deciding on DNA repair or apoptosis [ 23] based on whether the modification is removed to allow access to the MDC1 complex or retained resulting in activation of the JNK pathway [ 24].
More suggestions(15)
modifications are used
modifications are summarized
modifications are discussed
modifications are bolded
modifications are described
modifications are attenuated
modifications are presented
modifications are outlined
modifications are needed
modifications are called
modifications are proposed
modifications are accompanied
modifications are catalyzed
modifications are recommended
modifications are made
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