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Detachment-controlled models satisfactorily describe the deformation in coarse-grained ODS-NiAl, but modifications are necessary for fine-grained material.
Histone modifications are necessary for the induction of host transcription programs, commonly known as the "histone code" [20], [21].
These modifications are necessary for the proper secretion and activity of the morphogens (Miura and Treisman, 2006), and require specific mechanisms for Wnt and Hh secretion and spreading.
Thus, such protocol modifications are necessary for each new bacterial species tested (" strain- and matrix-specific optimization of the protocol") [ 10, 97, 105, 106].
Analysis by confocal microscopy confirmed previous observations and showed that all lipid modifications are necessary for optimal recruitment of GFP-H-RasG12V to the PM.
Posttranslational modifications occur in the N-terminal region, that is, blockage of the N-terminal amino group, palmitoylation, and phosphorylation, but none of these modifications are necessary for catalytic activity or immunogenicity so in theory the protein can be produced using any expression platform [ 11].
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The delay from the first biogenic production of oxygen and the permanent oxidation of Earth's atmosphere during the early Paleoproteorozoic Great Oxidation Event (GOE) indicates that significant environmental modifications were necessary for an effective accumulation of metabolically produced oxygen.
While alone IFN-γ-treatment did not significantly increase the expression of the non-classical MHC class I molecule HLA-G, cells treated with epigenetic inhibitors alone or in combination significantly augmented HLA-G expression, inferring that epigenetic modifications were necessary for the correct expression of HLA-G.
These modifications were necessary for the circularization of linear TFO.
Some assay modifications were necessary for accurate quantitation of viral load.
The results indicated that some suitable modifications were necessary for the items of Emotional Needs subscale.
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