Sentence examples for modifications are major from inspiring English sources

DNA replication timing, 3D chromosomal conformation, and several histone modifications are major covariates of position effects.

This result is in line with a recent study that two kingdom-specific tRNA modifications are major contributors that separate archaeal, bacterial, and eukaryal genomes in terms of their tRNA gene composition.

Although it is generally undisputed that bifurcating speciation events and descent with modifications are major forces of evolution, there is a growing belief that reticulate events also have a role to play.

Allostery and covalent modification are major means of fast-acting metabolic regulation.

If the modification was major or if the indicator was judged uncertain, it was resubmitted for a second round of validation.

Post-translational modifications of histones are major players in epigenetic control.

DNA methylation and histone modifications are two major epigenetic events regulating gene expression and chromatin structure, and their alterations are linked to human carcinogenesis.

These modifications are the major factors which promote protein aggregation and may contribute to progression of lens opacification.

However, as less than 10% of intracellular cisplatin accumulates on DNA, cytotoxicity and alternative cell death pathways caused by additional Pt modifications are a major interest.

Lysines, with their short side chain and positive charge, are critical for histone ionic interaction with DNA, and we find that this interaction is decreased with the introduction of a bulky negative charge from LG. Covalent histone modifications are a major method of controlling gene expression.

Both steps are major modifications of earlier Bush administration pronouncements.