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However, knowledge on the risk of these editing tools is insufficient especially when modifications are heritable.
It is clear that at least some epigenetic modifications are heritable, passed from parents to offspring in a phenomenon that is generally referred to as epigenetic inheritance, or passed down through multiple generations via transgenerational epigenetic inheritance.
Epigenetic modifications are heritable, reversible alterations in gene expression, which do not affect gene sequence.
This definition does not take into account whether epigenetic modifications are heritable or causal.
Epigenetic modifications are heritable changes affecting gene expression without altering the DNA sequence.
Although histone modifications are generally recognized as epigenetic modifications, not all histone modifications are heritable [ 29].
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Epigenetic modifications being heritable and adaptable at the same time may prove to make a significant contribution to BEN development and may be the link between the effect of environmental factors and genetic composition in BEN progression.
The modification is heritable, which separates biological evolution from the evolution of non-living things.
It also does not apply to genome editing in human somatic (non-reproductive) cells to treat diseases, for which patients can provide informed consent and the DNA modifications are not heritable.
Moreover, these epigenetic modifications are potentially heritable, conferring the same advantages to the offspring.
Epigenetic modifications are mitotically heritable changes of gene function in the absence of alterations in nucleotide sequence.
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