Sentence examples for modifications are frequently from inspiring English sources

This is not always the case, and in exact treatments of these equilibria two modifications are frequently necessary.

Alternative splicing and posttranslational modifications are frequently used to tune the IDP functionality.

Moreover, in cancer, aberrant epigenetic modifications are frequently found to be responsible for the silencing of tumor suppressor genes.

Altered DNA methylation, microRNA expression, histone, and chromatin modifications are frequently noted in meningiomas bearing prognostic and therapeutic relevance.

Furthermore, multiple intra-nucleosomal or inter-nucleosomal histone modifications are frequently observed within the same genomic loci.

Signaling sequences and sites of posttranslational modifications are frequently, or very likely most often, located within regions of intrinsic disorder.

As described in previous studies, a correlation between local DNA methylation and histone modifications is frequently observed in epigenetic-mediated gene silencing [ 46, 47].

Dosing modifications were frequently used to manage AEs, with 80% of patients having temporary treatment discontinuations and/or dose reductions of one or both study drugs due to AEs.

Dose modifications were frequently required (postponement of at least one cycle: 33 patients; dose reduction during at least one cycle: seven patients; discontinuation of a drug during at least one cycle: seven patients; premature discontinuation of at least one cycle: 13 patients).

Dose reductions and/or modification were frequently required in all three studies, whereas in the POCHER trial an amendment with doses reduction was mandatory for the continuation and completion of the study.

Correlations arise from crosstalk among modifications and are frequently attributed to protein protein interactions that recruit enzymes to existing histone modifications.