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Software architecture modifications are common rather than the exception in software development.
For robust audio watermarking, geometrical modifications are common operations and present many challenges because they severely alter the tempo or spectral structures of the audio and thus cause watermark desynchronization.
These modifications are common adaptation reactions also observed in the plant model Arabidopsis, thus representing key potential biomarkers and critical intervention points for improving LT tolerance of crop plants in cold regions with short summers.
Epigenomic dysregulation, such as methylation of DNA at CpG rich islands in promoter regions and histone-tail modifications are common in cancer cells [7] [9] as well as in melanomas [10].
Indeed, cell-envelope modifications are common in bacteria exposed to acid stress [ 165- 167].
Abnormal patterns of histone modifications are common findings in malignant cells.
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Dose modifications were common in these patients.
The use of tandem mass spectrometry to discover new protein post-translational modifications is common [ 34].
This does not appear to be the case for patients in the pre-HAART era, where dose modifications were common (Sridhar et al, 1992; Hoffman et al, 2000).
Loss of genes involved in tRNA modifications is common among small genomes of obligate endosymbionts (de Crécy-Lagard et al. 2012).
These profiles of active modifications were common among PS/RS active genes, PS active genes, and constitutively active genes, suggesting that PS-specific gene activation is regulated by a similar epigenetic mechanism with that of constitutively active genes in PS (Fig. 4b, Additional file 1: Figure S4).
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