Sentence examples for modifications and methylation from inspiring English sources

Additionally, tiling arrays have been recently applied to the study of histone modifications and methylation of cytosine bases (DNA methylation).

Epigenetic processes include histone modifications and methylation of CpGs (cytosine-guanosine dinucleotides) on the DNA, especially on gene promoters.

Genes are epigenetically regulated by a combination of histone modifications and methylation of CpG dinucleotides near their promoters [ 1, 2].

As mentioned above, DNA methylation is one of the most common epigenetic modifications, and methylation at specific CpG islands can provide insights into disease diagnosis.

Of these, 115/131 patient samples had sufficient DNA for bisulfite modification and methylation analyses.

MGMT promoter methylation status was obtained by using bisulfite modification and methylation-specific PCR (MSP).

Bisulphite-modification and methylation-specific PCR (MSP) were performed as previously described [ 22, 24, 25].

A large number of potential regulatory sequences also exhibit a high degree of dynamics in chromatin modifications and DNA methylation.

In this regard, we found that CD133 transcription is controlled by both histone modifications and promoter methylation.

In the cellular context, we compare this phenomenon with embryogenesis and normal development which are both regulated by epigenetic changes, such as histone modifications and DNA methylation and demethylation.

The CM was used for linking chromatin modifications and DNA methylation to generate the CM profile.