Sentence examples for modifications and factors from inspiring English sources

H3-K4 and H3-K27 methylation patterns represent only a part of the complex interplay of modifications and factors involved in chromatin structure and gene regulation [73], [78] underscoring the importance of more detailed analysis of other histone marks and transcription factor interactions at individual promoters.

We are presently developing mathematical models that integrate chromatin accessibility, chromatin modifications and transcription factors to predict gene expression patterns specific for a given cellular differentiation state.

It will be interesting to determine whether such histone modifications and interacting factors also influence rRNA gene expression through FACT.

Of these we distinguish Histones (and more particularly their post-translational modifications) and Transcription Factors (TFs).

Figure 2 presents a model of known and speculated NER-associated chromatin modifications and the factors that are involved.

This was done by integrating position of histone modifications, and transcription factors' binding sites at multiple intervals.

CpG methylation, histone modifications, and transcription factors very likely regulate in concert transcription of HML-2 LTRs.

In conclusion we find that ChIP-seq of histone modifications and transcription factors is a powerful method to study disease mechanisms on tissue samples.

Previous studies have shown that histone modifications and transcription factors tend to occur near or just in the DNase I hypersensitive sites [ 8, 13].

At distal regulatory regions that are marked by histone modifications and transcription factors, H3.3 steady-state levels are substantially higher in proximal regions compared to distal regions.

To account for the background of each individual ChIP, normalization was made to two intergenic sites devoid of known histone modifications and chromatin factors.