Sentence examples for modifications and expression from inspiring English sources
Aberrant changes in epigenetic mechanisms such as DNA methylation, histone modifications and expression of micro RNAs play an important role in cancer and contribute to malignant transitions.
The molecular targets are derived from mutated genetic components (e.g., DNA damage, hypo-, hyper-methylated epigenetic modifications and expression products).
Similarly, in HeLa cells 19S ATPase subunits regulate chromatin modifications and expression at the CTIIA and MHC-II promoters [40].
In summary, data included in this report have depicted a genome-wide blueprint of H3K9Ac/H3K9Me2 modifications and expression profiles for human MSC osteogenic differentiation.
The figures show the average epigenetic modifications and expression levels for the genomic regions summarized in each node.
Changes in site-specific phosphorylations, other protein modifications and expression levels of many signalling proteins were analysed using more than 400 different antibodies in Western blots.
Here we present a comprehensive analysis of the epigenetic landscape of heterochromatic genes across all the developmental stages of Drosophila using the available histone modification and expression data from modENCODE.
The ability to alter the epigenetic modification and expression of SHANK3 by environmental factors suggests that SHANK3 may be a valuable biomarker for dissecting the role of gene and environment interaction in the etiology of ASD.
Pathway splitting and coculture could be combined with an increase in gene dosage and modification and expression of a statin pump protein in the future, and this strategy may further improve lovastatin production.
However, it has been reported that there are differences in the epigenetic modification and expression of genes between iPSCs and ESCs and the expression of exogenous pluripotent factors is likely to cause tumors (Okita et al., 2007; Bock et al., 2011; Menendez et al., 2011).
Here we report the molecular cloning of seven v-rDNAs, and the characterization of their copy numbers, sequence, epigenetic modification, and expression profiles in multiple tissues.
