Sentence examples for modification we identified from inspiring English sources

Of the sites of modification we identified in the study, 16% have been reported in the literature.

Using a peak detection algorithm with a false discovery rate (FDR) of ≤0.1 for each modification, we identified a total of 8435 H3K4me3-enriched promoters and 3199 H3K27me3-enriched promoters (Figure 4B).

Within our panel of epigenetic modifications we identified a subset of marks that are associated with enhancer activity.

By applying the same strategy but with a different metric, that of pathway modifications, we identified one pathway that significantly and consistently stratified prognosis across the TCGA set and the two additional validation sets.

Furthermore, for histone modifications we identified differentially enriched peaks i.e. that were high in disease and low in normal tissue, or vice versa, and some of the associated genes have previously been implicated in the disease whereas others should be further studied as etiological candidates.

Using a cutoff of 1.00 and above for model-generated modification indices, we identified six items showing evidence of noninvariance across gender, three items showing noninvariance across management status, and three items showing noninvariance across educational levels.

The most frequent posttranslational modifications (PTM) we identified were as follows: mono-oxidation, pyrrolidinone, 4-hydroxynonenal (HNE), carboxymethyl, carboxethyl, glutamic semialdehyde (Glu SA), and 3-deoxyglucosone.

Using big-PI predictor for GPI modification site prediction, we identified a potential GPI modification site at the C-terminus of SOCS6 at Asn. Mutagenesis was performed to generate a SOCS6-N524L mutallelelele.

Transcription factor binding site polymorphisms are correlated overall with differences in local histone modification, and we identify specific transcription factors whose binding leads to histone modification in LCLs.

In addition to ubiquitous proteins that underpin fundamental cellular processes such as energy metabolism, transcription and translation, protein modification and transport, we identified a large complement of epithelial intermediate filament keratins, several ECM proteins and glycoconjugates, and a number of skeletal muscle thick filament proteins.

To set the stage for compound modification and yield optimization, we identified the biosynthetic gene cluster, used synthetic biotechnology approaches to establish and improve heterologous production, and generated analogs by pathway genetic engineering.