Sentence examples for modification we developed from inspiring English sources

Based on this protein modification we developed a novel, enzyme-linked sandwich immunoassay for the quantification of oxidised Pin1 (oxPin1) in human brain tissue samples.

To get a better handle on evaluating oxidative protein modifications, we developed a highly sensitive and fully quantitative mass spectrometry-based redox technique (i.e., OxICAT) that allows us to determine the in vivo oxidation status of hundreds of different protein thiols in organisms and to identify the proteins affected (Leichert et al., 2008).

To facilitate use of OPEN ZFNs for genome modification, we have developed ZFNGenome, a resource that displays potential ZFN target sites in a genome browser built on the user-friendly GBrowse platform [ 36].

The ABM of inflammation and tissue damage/healing was a modification of one we developed previously to address the prototypical wound healing scenario, namely skin healing [97].

Using genetic modification and functional selection, we developed a novel biosorbent from Genetically Engineered Bacillus subtilis (GEBS) cells.

In order to study this diverse pool of possible miRNA post-transcriptional modifications, we have developed Chimira.

In order to develop a more efficient means of isolating mutations which specifically disrupt dimerization of these transmembrane segments without affecting their membrane-targeting properties, we developed a modification to the original TOXCAT design in which the C-terminal maltose binding protein moiety is replaced by the β-lactamase.

To eliminate the arbitrariness of the background subtraction in method 1, we developed a modification of the co-localization approach described by Manders et al. (1993), using the MATLAB software (The MathWorks, Inc., R2006b).

In this study, using Illumina high-throughput sequencing of maize transcriptomics, chromatic H3K27me3 histone modification and DNA methylation data, we developed a new computational framework to identify allele-specifically expressed genes by simultaneously tracking allele-specific gene expression patterns and the epigenetic modification landscape in the seedling tissues of hybrid maize.

We developed a modification of cross-validation in which 1 case and 1 control were omitted from the small data set, a model was fitted to the remaining observations, and the fitted model was then used to predict the probability of the outcome in each member of the omitted pair.

To explore the regulatory potential for tRNA modifications in cellular stress responses, we developed a systems-oriented LC MS platform to measure changes in the relative quantities of all tRNA modifications in an organism.