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The fixed modification was set to carboxyamidomethylation of cysteine.
The variable modification was set to oxidation of methionine.
A fixed modification was set to carbamidomethylation of cysteine and a variable modification was set to oxidation of methionine.
Variable modification was set for methionine with the addition of 15.999 Da to represent methionine oxidation.
In addition, the number of hits for this modification was set in relation to the overall number of peptide hits within the peptide under investigation.
Full tryptic specificity was applied, two missed cleavages were allowed, and static modification was set for the alkylation of Cys with iodoacetamide (+57).
Similar(52)
The rates of PKC modification were set by fitting data of the timecourse of IRS tyrosine phosphorylation from human adipocytes [ 27].
Variable modifications were set to include oxidation of methionine and Gly-Gly addition to lysines, fixed modifications were set to include carbamidomethylation of cysteine residues.
Epigenetic modifications are set by cell-type specific transcriptional regulators and chromatin remodelling enzymes [3].
The fixed and variable modifications were set to Carbamidomethyl (C) and oxidation (M) respectively.
Variable modifications were set to methionine oxidation, pyro-glutamate formation of amino terminal glutamine, acetylation of the N-terminus, deamidation of glutamine or asparagines.
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