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Occasional use of oral pain medications and activity modification was required.
The lipid modification was required for the association since the association of Eu-rVsp1 was similar to that of Eu-albumin and media alone and much lower than that of Eu-LVsp1 (Figures 6B&C).
Dose modification was required in 22 (40%) patients.
Dose modification was required for six cycles (4%).
For each modification, the fit indices were again examined to determine whether further modification was required.
Importantly, this modification was required for SIRT6-mediated stimulation of DSB repair.
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Therefore, further surface modification is required to enhance nanotube cell interaction.
Hydroxylation modification is required for binding of the von Hippel-Lindau (VHL) protein, which targets HIF-1α and HIF-2α for ubiquitination and proteasomal degradation15.
In summary, mammalian mitochondria use folate-bound one-carbon units to methylate tRNA, and this modification is required for mitochondrial translation and thus oxidative phosphorylation.
Specifically, the authors2 report that, in mouse cells, the enzyme CUL3 KLHL12 adds a single ubiquitin to a small pool of SEC31 molecules, and that this modification is required to drive the secretion of collagen.
In addition, BNNT films are usually extremely nonwettable to water, so surface modification is required before they can be used in bioapplications.
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