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A fixed modification was indicated for cysteine carbamidomethylation. Full trypsin specificity was required.
An effect modification was indicated for the combination of GCLC-129 and GSTP1-114 (Table 4), where subjects with zero or one variant allele demonstrated a steeper regression slope compared with individuals with two variant alleles.
Before 2009, dose modification was indicated if both major (swollen joint counts (SJC) >1 and elevated erythrocyte sedimentation rate (ESR) or C-reactive protein (CRP)) or one major and two minor criteria (tender joint counts (TJC) >1, morning stiffness >30 minutes, pain on visual analogue scale (VAS) >30 mm, fatigue VAS >30 mm) were fulfilled (criteria-based DMC) [ 2].
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The external surfaces showing textural modification are indicated by 'Rim.'.
The external surface showing structural modification is indicated by an arrow.
The hypertension guidelines state 'Lifestyle modification is indicated for all patients with hypertension, regardless of drug therapy'[ 13].
The lysine residues carrying the GlyGly modification are indicated in bold and the superscript is the position in the protein sequence.
Lifestyle modification is indicated for all hypertensive patients; however, it rarely reduces blood pressure sufficiently and recent data underscore the importance of rapid blood pressure control (Julius et al. 2004).
These modifications are indicated in Text S2 and the modified matrix is given in Text S3.
However, for type 2 diabetes, effect modification by sex was indicated, with stronger associations among women.
In addition to DNA methylation, the importance of histone modification in PLA2R1 regulation was indicated by the synergistic re-expression of PLA2R1 after simultaneous treatment of MDA-MB-453 cells with DNA methylation and histone deacetylase inhibitors (Fig. 2).
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