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Although signal-dependent mechanisms of resistance would be thwarted by the first barrier described above (e.g., efflux pump overexpression, QSI degradation, or target protein modification to become immune), additional mechanisms of resistance are conceivable that would not require quorate levels of native signal in order to express the QS regulon.
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The next section illustrates that existing forest stand growth models require some fundamental modifications to become suitable for both monocultures and mixed-species stands.
The Notch protein is synthesized as an inactive precursor that has to be cleaved three times and to undergo various post-translational modifications to become active [ 19- 22].
Lamin C2 has an alternative exon 1 compared with lamin C and is present in germ cells. 1 Lamin A proteins contain CaaX boxes at their C-terminal ends; they are synthesized as prelamin A proteins, which undergo farnesylation and other posttranslational modifications to become mature proteins.
In 1993, P-Orridge's life took yet another interesting turn when s/he met Lady Jaye, with whom s/he would apply Brion Gysin and William S. Burroughs' cut-up technique to body modification, attempting to become one being through the Pandrogeny Project.
Translated proteins are often subjected to post translational modifications (PTMs) to become functionally active.
"Many trial modifications have failed to become permanent modifications.
Mixed models Even if the medical model of illness is wrong, it may only require a small modification in order to become acceptable.
In addition to the induction of its protein synthesis, phosphorylation is a critical posttranslational modification for Atg32 to become active for mitophagy.
aUPD regions may cause pre-existing abnormalities (mutation, deletion, amplification, methylation, histone modification, and/or imprinting) to become homozygous, which may lead to clonal selection and growth advantage in the cells.
As mentioned above, LC3-I undergoes post-translational modifications by PE to become LC3-II [ 30– 30].
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