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Ubiquitination of protein is an indispensable post-translational modification that serves as a component of the protein quality control system.
5-Methylcytosine (5mC) is an important epigenetic modification that serves as a marker for gene expression, X-chromosome inactivation, and transposon silencing, among other developmental processes.
Protein S-glutathionylation is a reversible post-translational modification that serves, in addition to regulatory and signaling functions, as a protective measure against irreversible oxidation of cysteines.
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Eukaryotic transcription is accompanied by combinatorial chromatin modifications that serve as functional epigenetic markers.
Protein ubiquitin tags are post-translational modifications that serve to either target substrates for proteasomal degradation or modify their interactive capacities [ 1].
In contrast, cellular hypoxia occurs frequently, both physiologically and pathologically, and serves as a potent stimulus for changes in gene transcription, translation, and several post-translational protein modifications that serve to rapidly adapt cells and tissues to this stimulus.
Acetylation of α-tubulin is a post-translational modification of microtubules that serves as a recognition signal for the anchoring of molecular motors and, as such, underlies the transport of various proteins or organelles in neurons.
They are thought to be storage, assembly and modification compartments that serve to supply proteins to active transcription sites.
Taking into account the various modifications that can occur simultaneously on a nucleosome, in particular at the N-terminal histone tails, it is conceivable that these modifications create a specific pattern that serves as a receptor-like docking station for regulatory factors that recognize and somehow interpret the modification signals.
Acac serine phosphorylation on Ser80, a post-translational modification catalyzed by AMP-dependent kinase that serves as a feedback control on enzyme activity, was increased in both slc16a6a mutant groups (Brownsey et al., 2006).
However, if you are clever, you can come up with two modifications of the construction for star that serves for ?
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