Sentence examples for modification that promotes from inspiring English sources

Specifically, this occurs by disrupting the phosphorylation of Ser2 in the C-terminal domain (CTD) of Pol II, a post-translational modification that promotes transcriptional elongation of the polymerase.

Here, initial activation of IRF3 is mediated by the TRIM25 or Riplet/RNF135 ubiquitin ligases, inducing RIG-I ubiquitylation vis Lys 63- linked ubiquitin polymers, a modification that promotes its association with MAVS, initiating downstream IFN production [46].

Together these data demonstrate a communication flow, where the signal from the soma (ecdysone signaling-cell adhesion) induces in the germline a transition from stemness to differentiation, which requires a specific histone modification that promotes the expression of differentiation genes, enabling efficient GSC progeny differentiation (cell adhesion-Wg signaling-H2Bub1-Bam) (Fig. 6).

With dextran-based surface coatings, it will be possible to develop well-defined surface modifications that promote specific cell interactions and perhaps better performance in long-term biomaterial implants.

Eukaryotic messenger RNAs possess characteristic 5'- and 3'- modifications that promote the overall functionality of the molecule.

Here, we looked for synthetic interactions between the splicing factors and the elongation factor TFIIS (DST1), which is synthetically lethal in combination with bur2Δ [52]; SPT4 whose activity is regulated by the Bur complex [43]; and LEO1, a nonessential member of the PAF complex [52], [53] responsible for regulating histone modifications that promote active transcription.

Without Arm, Lef/TCF/Pan together with their cofactors recruit histone deacetylases, triggering chromatin modifications that promote transcriptional silencing (Saito-Diaz et al., 2013).

Readjustment of heterotypic (soma-germline) cell adhesion modulates Wg signaling intensity in the germline, which in turn regulates histone modifications that promote expression of the genes necessary to trigger early germline differentiation.

Taken together, these results suggested that the interaction between Spp1 and Mer2 could occur independently of Set1 raising the intriguing question of the key regulatory modifications that promote Spp1 association to Mer2 at the expense of the one with the Set1C (Fig. 3).

Another explanation is that reduced long-distance dispersal is an evolved adaptive modification by bacterial infections that promotes their own transmission.

The present, and previous [29], [45], findings suggest further that Gro/TLE activity may be controlled by antagonistic post-translational modifications that either promote (cofactor-activated phosphorylation) or inhibit (HIPK2 and/or MAPK-mediated phosphorylation) its function.