The deletions and rearrangements should occur only with gene-editing techniques that rely on DNA cutting, not with some other types of CRISPR modifications that avoid cutting DNA, notes Hsu.
However, this article needs some modifications that avoid to be published in its current version: All of the gene acronyms may be written italics.
Similar to commonly employed practices for stress ulcer and deep venous thrombosis prophylaxis, strategies targeting risk factor modification (that is, avoiding a 'second-hit') in at-risk patients have the potential to substantially reduce rates of ALI.
Future studies should be designed with schedules and dose modification provisions that avoid unnecessary CPT-11 dose reductions to exploit more directly the therapeutic synergy of these agents.
Yet Moreno, who spent years studying rural colonization, knows that carrots and sticks are behavior modification tools that avoid confronting root causes.
A one-word modification that shifts everything.
Oligonucleotide-based detection schemes that avoid chemical modification possess significant advantages, including simplified design, intrinsic affinity for targets, low cost and ease to extend applications.
SPCA is a modification of PCA that avoids this characteristic by explicitly incorporating information on the relationship between the predictor variables and the response.
We derived natural history parameters describing the pathogenesis of tuberculosis in the model from studies of populations before widespread tobacco use, to avoid confounding our modifications that accounted for smoking (table 1).
Early diagnosis of diabetes, before the onset of clinical symptoms, would favour the implementation of lifestyle modifications that could retard its progression and avoid the development of atherosclerotic lesions.
