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These mechanisms rely on reversible modifications of DNA (most commonly DNA methylation and histone modification) that affect gene expression without altering the DNA sequence.
Accumulating evidence from studies on DNA methylation and histone modification that affect chromatin structure, as well as on the role of microRNAs in regulating mRNA levels supports the contribution of epigenetic mechanisms to the development of FASD.
Fatty acids serve as precursors for synthesis of cellular lipids, as lipid bilayer constituents that affect membrane fluidity and architecture, and as substrates for post-translational protein modification that affect protein localization and activity.
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The influence of fluoride ions on TiO2 surface was analyzed by XPS technique, revealing a surface modification that affects the performances of the catalyst.
This research paper explain the CAD Management Model, which enable us to better manage the Digital Mockup (DMU) and propagate changes to the hole assembly after a modification that affects one of its component, that has been sent to a partner modified an then reinserted.
Poly(ADP-ribosyl)ation is a transient post-translational modification that affects mostly chromatin-related proteins.
Although the mitotic modification that affects Aur-A stabilization was discovered, the physiological dynamics and its regulation remains incompletely understood.
RNA editing is a major post transcriptional modification that affects global gene expression and tends to occur at high levels in hESCs.
Proteolysis is an irreversible post-translational modification that affects every single cell of an organism.
Prolyl hydroxylation is an important post-translational modification that affects the structure and function of proteins.
Another post-translational modification that affects the charge of a protein is acetylation.
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