Sentence examples for modification systems are from inspiring English sources
Restriction modification systems are a way for bacteria to control the uptake of foreign DNA.
Restriction modification systems are subject to frequent LGT and are often associated with mobility elements like phage [89].
CRISPR might mediate antagonism between genetic elements; just like Toxin-Antitoxin and restriction and modification systems are used for competition between plasmids.
Elaborate manners of regulation, such as interacting DNA-methylation and histone modification systems, are likely to be the hallmarks of the epigenetic code.
To address the functional consequences of SUMO modification of mutant HTT on disease, the involvement of SUMO-1 and SUMO-2 modification on the formation of insoluble HTT species was evaluated in HeLa cells, where SUMO modification systems are highly active.
The primers used to detect the CRISPR elements and restriction modification systems were designed based on DPC6026 with at least 2 different specific combination of primers used (Table S1).
Type I restriction modification systems were found in B. cereus ATCC 14579 and ATCC 10987, but not in B. anthracis [37], and they occur only rarely in the B. cereus group.
Thirty-one putative restriction modification systems were identified in the Shi470 genome sequence (see below), usually by specific methylase signatures, in accord with the great abundance of such gene clusters in other H. pylori strains (http://tools.neb.com/~vincze/genomes/).neb.com/~vincze/genomes/
The inhibitor study is the first of its kind, and a proof of concept that modulation of chromatin modification systems is of potential therapeutic benefit in controlling proinflammatory mechanisms.
Type1 restriction modification system are intriguing multifunctional multisubunit molecular motors that can catalyze both restriction and modification activity.
For example, genes encoding a restriction modification system are found in GI-i, which we suggest is a putative prophage (see section on DNA secretion system).
