Sentence examples for modification studies have from inspiring English sources

Furthermore, achieving sustainable change in the clinical environment has not been extensively investigated as behaviour modification studies have been undertaken over short durations, with follow-up assessments conducted after the immediate intervention period.

Since α,γ-diketo acid (DKA) compounds were identified as potent and selective inhibitors for HIV integrase, numerous structural modification studies have been carried out to search for a clinical candidate as a supplement for the highly active antiretroviral therapy regimen.

Certain varieties contain more than others, and some selective breeding and genetic modification studies have focused on using this trait to identify and produce commercial varieties with increased pest resistance.

Previous chemical modification studies have revealed that none of CTs' loops is exclusively responsible for biological activities of the toxins [45] [47].

Our substrate modification studies have revealed occult epoxidase and 21-hydroxylase activities of CYP17A1, and the fraction of epoxide formed correlated with the 16α-hydroxylase activity of the enzymes.

However, Abian and co-workers [ 6] focused their mutations on a lysine-rich area of Pencillin G Acylase, which previous chemical modification studies had proven not to be critical for protein stability, and so minimised the chance of a deleterious mutation in this area.

Also, a site-directed chemical modification study has provided strong evidence that α4 lines the lumens of the pores formed by the toxin [ 34].

The application of ChIP-Seq to histone modification study has proved very useful for understanding the genomic landscape of histone modifications (Barski et al., 2007; Mikkelsen et al., 2007).

Related to this finding, recent chromatin modification mapping studies have revealed that histone H3 Lys4 mono- and dimethylation (H3K4me1/2) at enhancers is associated with transcriptionally active genes [ 57, 83].

Taking into account the potential clinical importance of the oxidative modification of LDL, many studies have been carried out to quantify their in vitro susceptibility to oxidation.

Structural modifications guided by structure activity studies have resulted in the identification of potent compounds.