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In 2003, 2004 and 2006, symposium interventions of content modification (lecture topics/workshops), audience modification (smaller groups, designing workshops for different levels of providers) and in-process modification (modification of lecture technique in two sequential 2006 symposiums) were done.
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Epigenetic mechanisms in humans are post-transcriptional histone modification, small and other non-coding RNAs (siRNA and miRNAs) and DNA methylation as depicted in Fig. 2 [11].
We did not, however, find any significant effect modification (smallest P value 0.19 for the interaction by age).
As none of the interaction terms indicated statistically significant effect modification (smallest P value 0.063), we proceeded without considering these interactions.
Thus, some modifications (smaller dimension) were required in the modeling process.
Surprisingly, in the ΔXT/FT mutant, which lacks plant-specific core modifications, smaller amounts of bisecting glycoforms were synthesized as compared to wild-type plants [46].
These latter include DNA methylation, histone modifications, small, non-coding RNAs, and factors involved in the regulation of chromatin architecture [ 34- 36].
Accumulating evidence demonstrates that HIF-1 is a target of epigenetic regulation such as the DNA hypermethylation of gene promoters, histone modifications, small interfering RNAs and microRNAs [ 32].
However, after PAP film modification, a smaller semi-circle was obtained which meant low electron-transfer resistance.
Modification means smaller cash flows but also fewer defaults.
Pharmacotherapy, stent design modification, or smaller stent diameter may increase the utility of stents after brachytherapy.
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