Sentence examples for modification sites detected from inspiring English sources

(C ) The number of modification sites detected as a function of the number of DNA reads.

DOI: http://dx.doi.org/10.7554/eLife.05198.008 10.7554/eLiFigure98.009 Figure 2 figure supplement 5. Number of modification sites detected as a function of the amount of DNA and RNA reads.

The constructed squid coding sequences and all the A-to-G modification sites detected in the coding regions of the squid are available via Dryad digital repository (Alon et al., 2015; http://dx.doi.org/10.5061/dryad.org/10.5061/dryad

The differential chromatin modification sites were detected by diffReps [ 42] using default parameters and the FDR cutoff was set as 0.1.

Overall, 81,930 weak and 5649 strong A-to-G modification sites were detected in 7776 ORFs, and only 12,403 weak and 254 strong non A-to-G modifications sites (the modification sites and their number of supporting reads in all the tissues studied are tabulated in Alon et al. (2015) available via Dryad digital repository).

The data for S. p snoRNAs were cited from Luo (2004) [ 38]. "Undet" indicates that the snoRNA has not been identified in the human genome although the corresponding modification site was detected.

In 45CBS, we identified 50 labeled residues in total, and we found only 4 modification sites which were not detected in wtCBS (Table 2).

Based on this prototype instrument, we plan to construct a fully functional model of the mass spectrometer for detecting modification sites on proteins and profiling their abundances with high speed and sensitivity.

Multiple alignment of protein sequences and visualization of the detected post-translational modification sites were performed using CLC Sequence Viewer (CLC Bio).

With the exception of labeling with NBS, all other modification sites were identified by detection of labeled peptides that were not detected in unmodified controls (27); expected mass shifts for each reaction are shown in Supporting Information Table S1.

diffReps is a powerful program to detect differential chromatin modification sites using ChIP-seq data [ 42].