A large number of other histone modifications serve a number of regulatory and other functions (reviewed in [ 33]).
Thus, both DNA methylation and histone modifications are generated by targeted recruitment of enzymatic activities, and these modifications serve a reinforcing, but not instructive, role in maintaining epigenetic states.
Moreover, such a modification serves as a first step towards the modelling of higher particle concentrations.
In fact, this modification serves as a docking site for SUV39H, which contains a specialized domain called the chromodomain, able to bind to H3K9me3.
The strong linkage disequilibrium between Arg72Pro and polymorphisms PIN3 (P < 0.0001), rs12947788 (P = 0.0003), and rs12951053 (P = 0.0003) confirms the findings of other studies [ 63, 64] and demonstrates that the modification serves as a marker of susceptibility and not as a consequence of mutational low doses of ionizing radiation.
We show that GPI modification is necessary and sufficient for delivering both BG_pap and PDCB1 to Pd Moreover, the GPI modification signal from both Pd- and non-Pd GPI-APs is able to target a reporter protein to Pd, likely to plasma membrane microdomains enriched at Pd As such, the GPI modification serves as a primary Pd sorting signal in plant cells.
It is thought that the H3K9me3 histone modification serves as a transcriptionally repressive mark.
The C-strep connector without N-terminus modification serves as a single connector control.
This histone modification serves as a reliable marker for active regulatory elements (Creyghton et al., 2010; Arvey et al., 2012).
This modification serves as a substrate for the elongation of anchored Lys63-linked polyUb chains, catalyzed by the heterodimeric E2 enzyme Ube2N/Ube2V2.
We believe that the finding of reduced Lys5-Me modification serves as a platform for further investigations into the functional differences between the two molecules and possibly for understanding the biological function of the H2B-Lys5-Me modification.
