Sentence examples for modification requisite from inspiring English sources

The underlying mechanism of pathway inhibition remains to be fully elucidated; however, it may depend on the palmitoylation of Wnt, a modification requisite for the activity of this protein (Clevers and Nusse, 2012, Fiorentino et al., 2008).

The experimental program is further supplemented by the system studies focused mainly to the process flow-sheet design and calculations and to the requisite modification of some apparatuses for the future verification of the process with irradiated fuel in hot conditions.

The unique ability of the star-like copolymer emanating from the methyl cholate core provided the requisite modification in the block copolymer interfacial curvature to generate vesicles of high loading capacity for DOX with significant kinetic stability that have potential for use as an anti-cancer drug delivery carrier for cancer therapy.

No modifications necessary.

We have therefore sought to develop scFv-targeted Ad vectors using a secreted scFv that undergoes the requisite posttranslational modifications and is trafficked for secretion.

The Darwinian scheme is simpler and less demanding than the Lamarckian one in that no specialized mechanisms are required to direct the change to the relevant genomic locus (loci) and restrict it to the specific modifications (mutations) providing the requisite adaptation.

Are the rRNA modifications a pre-requisite for incorporation into the subunit or do they occur as part of a quality control process?

Some modifications were necessary.

Permanence of H3K9me2 near the paradigmatic E2-responsive pS2 promoter in LSD1-interfered challengedlenged with 17 β-estradiol (E2) prevented addition of the phosphoryl group to the following site, revealing to represent a pre-requisite for that modification, thus upgrading the current version of the 'methyl/phos' switch theory (Supplementary Figure 1A).

We hypothesize that phosphorylation may be a requisite for O-GlcNAc modification and tyrosine phosphorylation plays a role in the interplay between O-GlcNAc modification and serine/threonine phosphorylation in proteins.

iii) Is phosphorylation a requisite for O-GlcNAc modification?