Sentence examples for modification represent a from inspiring English sources

In Arabidopsis, the genes encoding the enzymes that mediate Ub modification represent a significant fraction of the genome [ 2].

The use of LV/RVs for T-cell modification represents a manufacturing challenge due to the complexity of the transduction approach and the necessity of thorough quality control.

Targeted covalent modification represents a proven approach to drug discovery with the recent FDA approvals of afatanib, ibrutinib, and osimertinib agents, which were designed to undergo an irreversible hetero-Michael addition reaction with a unique cysteine residue of a specific protein.

Accumulating evidence indicates that epigenetic modification represents a molecular substrate for cellular stresses, either suppressing or promoting disease initiation [ 71].

From all that, it seems that tRNA modification represents a major enzymatic function of Elongator (Glatt and Müller, 2013).

Protein modification represents a potential target in the engineering of plants with the goal of increasing tolerance to multiple stresses.

While further evaluation of the safety and immunogenicity of this approach must be conducted, we demonstrate that Bromelain surface modification represents a valuable approach to provide synthetic particles with proteolytic activity toward tumor ECM.

Overall, these findings suggest that maternal lipid dysregulation and de novo lipogenesis have major effects on the developmental programming of offspring hepatic steatosis in the maternal obesogenic setting, with epigenetic modification representing a potential mechanism.

In addition, numerous epigenetic modifications represent a potential goal of novel therapeutic strategies and treatment design.

Thus, balanced and proportionate modifications represent a win-win situation for everyone.

These experiments prompt questions concerning the extent to which histone modifications represent a cause or a consequence of pluripotency.