Or perhaps a modification: 3 points for a win, 1 for a draw, 1 point for each goal scored up to 3; or leave the current scheme largely in tack but award no points for ties.
In total 1438 points for modification were cited (Table 4).
A Jadad score 50 with minor modifications (the two possible points for blinding were replaced with one point for the use of a blinded assessor) 51 was calculated for the economic evaluations that included a randomised trial.
Stomach fullness was assessed under a light microscope according to Hynes' [ 43] point method with minor modification, i.e., 4 points for 1/4 fullness, 8 points for 1/2 fullness, 16 points for complete (1×) fullness, and 32 points for twice (2×) fullness.
There are the obligatory bass and treble settings with adjustable crossover points for sound modifications in different types of rooms.
Therefore, inhibitors 1 and 9 represent important starting points for synthetic modifications and development into more potent noncovalent inhibitors of PBPs that can target penicillin-resistant bacteria.
Some points for minor modifications: When I read the title my first impression was that the manuscript compares the promiscuity of drugs with respect to their release data, e.g. "do more recent drugs show more or less promiscuity than older drugs".
(Double-blinding is impractical in Tai Chi studies, our modification gave 1 point for proper single blinding of the outcome assessor).
The reduction of native disulfide bonds provides a convenient method to access two nucleophilic cysteine residues that can serve as ideal attachment points for such chemical modification.
Two chemical modifications may be regarded as starting points for this field, namely, 2′-fluoro (2′-F) substitutions and phosphorothioate chemistry, since ONs with these modifications constitute versatile, synthetic analogs of the naturally occurring counterparts (Fig. 1).
