Sentence examples for modification plays essential from inspiring English sources
Post-translational modification plays essential roles in the most biological pathways and disruption of PTM sites is known as the major cause of diseases [ 7].
Dynamic nuclear SUMO modifications play essential roles in orchestrating cellular responses to proteotoxic stress, DNA damage, and DNA virus infection.
Epigenetic mechanisms such as DNA methylation and histone modifications play essential roles in cell differentiation and transcriptional regulation and are identified as key mediators of cancer progression.
Reversible lysine acetylation is one of the most important protein posttranslational modifications that plays essential roles in both prokaryotes and eukaryotes.
DNA methylation is an epigenetic modification mechanism that plays essential roles in diverse biological processes [ 1].
Glycosylation is one of the most important posttranslational modifications of proteins and plays essential roles in various biological processes.
Among the epigenetic modifications, cytosine DNA methylation is the best studied, and plays essential roles as an evolutionarily conserved genome defense device as well as a master regulator of genome-wide temporal and spatial gene expression [ 6, 7].
It plays essential roles in cell cycle regulation, transcription and DNA repair via epigenetic modifications.
It also plays essential roles in regulating inflammation [13 17].
Despite the fact that TFEB can be activated by its own stimulation in a transcriptional autoregulatory pathway (Settembre et al., 2013a), post-translational modification play an essential role in modulating TFEB activity, among which phosphorylation is the first to be studied.
Post-translational modifications (PTMs) of proteins play essential roles in almost all cellular processes, and are closely related to physiological activity and disease development of living organisms.
