Sentence examples for modification patterns have from inspiring English sources

Histone modification patterns have been shown to be critical for establishing and maintaining stable epigenetic states of genes in Arabidopsis.

Combinatorial histone modification patterns have been observed among the many possible modifications of histone tails.

However, histone modification patterns have been found to predict the risk of prostate cancer [ 24].

Numerous changes in modification patterns have also been observed at the level of posttranslational histone modifications [109].

Although tobacco has long been a classical object of genetic studies, its histone modification patterns have been rarely studied.

Similar to DNA methylation patterns, histone modification patterns have also been used to predict prognosis in multiple cancers.

HPV16 E7 protein has also been shown to induce expression of histone methyltransferase EZH2 expression in cervical cancer cells; however, the changes in the histone modification pattern have not been examined (Holland et al. 2008).

Early differentiation of stem lineages, explosive radiations, and abrupt modifications in developmental patterns have been proposed to be responsible for such a diversity [ 1, 2].

These results indicate that diffusion and low RE recruitment mechanisms give rise to modification patterns that have been observed at transcription start sites and promoters in genome-wide ChIP-seq studies [ 2, 5, 9, 20].

Based on the gene expression and chromatin modification patterns, we have predicted tens of thousands of potential core regulatory elements shared by all cell types and potential tissue-specific regulatory elements and show that a combination of both H3K4me1 and H2A.Z is a better predictor of enhancer activity than either alone.

Nevertheless, what type of effect distinct combinations of simultaneously occuring histone modifications (Histone Codes or patterns) have upon cellular events is poorly understood.